The Blaydon Race has partnered with a charitable foundation to honour a girl who died with a rare disease.
Nicole Rich from Throckley, Newcastle, died from complications from Batten disease in October, aged 11.
Now a foundation set up in her memory, the Nicole and Jessica Rich Foundation, has partnered with race organisers to raise awareness of the genetic disorder which causes a progressive deterioration of the brain and nervous system.
Nicole's family said they were "delighted and honoured" to be supported by such an iconic event.
The historic 5.8 mile (9.3km) race always begins at 18:15 BST.
The route, from Newcastle City centre to Blaydon, is based on the lyrics to the 1862 song by Geordie Ridley, The Blaydon Races.
International Batten Disease Awareness Day also falls on 9 June.
